Browsing by Author "Cai, Demin"
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Assessment of the Welfare of Working Horses: Combining Clinical Evaluations with Indirect Indicators
Basher, Abdallah A.; Ahmed, Abdelkareem A.; Pfukenyi, Davies M.; Essa, Mohamed Osman Abdalrahem; Husien, Hosameldeen Mohamed; Saleh, Ahmed A.; Adam, Saber Y.; Cai, Demin (MDPI, 2026-02-05)Assessing the welfare of the working horses is crucial for identifying health and management issues and implementing effective solutions. This study evaluated the welfare of working horses in South Darfur, Sudan, by ... -
Editorial: Integrated role of nutrition and digestive physiology for animal health, Volume II
Cai, Demin; Liu, Hao-Yu; Dong, Haibo; Ahmed, Abdelkareem A. (Frontiers Media, 2022-12-28)Integrating nutrition and digestive physiology is crucial for animal health and reproductive performance. The gastrointestinal (G.I.) tract plays a pivotal role in animal health in mammalian species. To perform its maximum ... -
Lactoferrin Attenuates Intestinal Barrier Dysfunction and Inflammation by Modulating the MAPK Pathway and Gut Microbes in Mice
Hu, Ping; Zong, Qiufang; Zhao, Yahui; Gu, Haotian; Liu, YaYa; Gu, Fang; Liu, Hao-Yu; Ahmed, Abdelkareem A; Bao, Wenbin; Cai, Demin (Oxford Academic, 2022-11)Background: Deoxynivalenol (DON) is a major mycotoxin present in staple foods (particularly in cereal products) that induces intestinal inflammation and disrupts intestinal integrity. Lactoferrin (LF) is a multifunctional ... -
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
Hu, Ping; Liu, Yaya; Li, Shicheng; Zhao, Yahui; Gu, Haotian; Zong, Qiufang; Ahmed, Abdelkareem A.; Bao, Wenbin; Liu, Hao-Yu; Cai, Demin (NLM (Medline), 2023-05-31)Deoxynivalenol (DON), one of the most common mycotoxins contaminating food and feed, has been shown to induce hepatotoxicity. Lactoferrin (LF) enriched in human milk is a critical functional food component and performs the ... -
Lithocholic Acid Alleviates Deoxynivalenol-Induced Inflammation and Oxidative Stress via PPARγ-Mediated Epigenetically Transcriptional Reprogramming in Porcine Intestinal Epithelial Cells.
Li, Yanwei; Zhu, Chuyang; Yao, Jiacheng; Zhu, Cuipeng; Li, Zhaojian; Liu, Hao-Yu; Zhu, Miaonan; Li, Kaiqi; Ahmed, Abdelkareem A.; Li, Shicheng; Hu, Ping; Cai, Demin (American Chemical Society, 2024-03-13)Deoxynivalenol (DON) is a common mycotoxin that induces intestinal inflammation and oxidative damage in humans and animals. Given that lithocholic acid (LCA) has been suggested to inhibit intestinal inflammation, we aimed ... -
Nuclear Receptor RORα/γ: Exciting Modulators in Metabolic Syndrome and Related Disorders
Gu, Haotian; Hu, Ping; Zhao, Yahui; Liu1, Yaya; Wang, Yi-Ting; Ahmed, Abdelkareem A.; Liu, Hao-Yu; Cai, Demin (Frontiers Media [Commercial Publisher], 2022-06-21)Under the influences of modern lifestyle, metabolic syndromes (MetS), including insulin resistance, obesity, and fatty liver, featuring a worldwide chronic disease, greatly raise the risk of type 2 diabetes, heart disease, ... -
Targeting Mycotoxin Toxicity: From Molecular Mechanisms to Nutritional Interventions
Huang, Shirui; Gao, Yiqin; Tyasi, Thobela Louis; Ahmed, Abdelkareem A.; Kim, In Ho; Liu, Hao-Yu; Adam, Saber Y.; Cai, Demin (MDPI, 2026-04-26)Mycotoxin contamination is an important threat to food and feed safety as well as human and animal health, with particular emphasis on oxidative stress, apoptosis, autophagy, inflammation, and dysbiosis. Mycotoxins represent ...







